The Shock of Aging: Molecular Chaperones and the Heat Shock Response in Longevity and Aging – A Mini-Review | Zendy

Stuart K. Calderwood | Zendy; Ayesha Murshid | Zendy; Thomas L. Prince | Zendy

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The Shock of Aging: Molecular Chaperones and the Heat Shock Response in Longevity and Aging – A Mini-Review

Author(s) -

Stuart K. Calderwood,

Ayesha Murshid,

Thomas L. Prince

Publication year - 2009

Publication title -

gerontology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.397

H-Index - 94

eISSN - 1423-0003

pISSN - 0304-324X

DOI - 10.1159/000225957

Subject(s) - hsf1 , longevity , heat shock factor , proteostasis , heat shock protein , microbiology and biotechnology , transcription factor , heat shock , biology , chaperone (clinical) , hsp70 , proteome , homeostasis , genetics , gene , medicine , pathology

Aging can be thought of as the collision between destructive processes that act on cells and organs over the lifetime and the responses that promote homeostasis, vitality and longevity. However, the precise mechanisms that determine the rates of aging in organisms are not known.

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