The Value of Levamisole in a Wilms’ Tumor Animal Model | Zendy

Zew Wajsman | Zendy; Patricia D. Williams | Zendy; G.P. Murphy | Zendy

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The Value of Levamisole in a Wilms’ Tumor Animal Model

Author(s) -

Zew Wajsman,

Patricia D. Williams,

G.P. Murphy

Publication year - 1978

Publication title -

oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.987

H-Index - 98

eISSN - 1423-0232

pISSN - 0030-2414

DOI - 10.1159/000225288

Subject(s) - levamisole , wilms' tumor , animal model , medicine , renal tumor , oncology , cancer research , kidney , nephrectomy

The effect of Levamisole was studied in an animal model of Wilms' tumor. No tumoridical effect of Levamisol could be documented in this tumor model, and no effect was shown on prevention of tumor, when Levamisole was given before tumor implantation. In previous experience with Wilms' tumor model, a good correlation between the human and animal tumor was found in regard to treatment with different drugs. The fact that Levamisole had no effect on our animal model and its reported immunosuppressive effect at some doses, should be considered in planning clinical trials.

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