New Approaches to Body Composition Research: A Reexamination of Two-Compartment Model Assumptions
Author(s) -
Steven B. Heymsfield,
Steven W. Lichtman
Publication year - 1990
Publication title -
transfusion medicine and hemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 39
eISSN - 1660-3818
pISSN - 1660-3796
DOI - 10.1159/000222544
Subject(s) - compartment (ship) , biochemical engineering , field (mathematics) , cornerstone , composition (language) , computer science , scale (ratio) , mathematics , engineering , art , linguistics , oceanography , philosophy , physics , quantum mechanics , pure mathematics , visual arts , geology
The field of human body composition research by necessity is based upon assumptions related to tissue chemical content. The 2-compartment model, which requires only 1 measurement in addition to body weight, is the cornerstone of current research in this field. Yet the assumptions upon which 2-compartment models are based were developed on a limited scale and their validity under specified conditions is questionable. Recent developments now allow quantification of previously unmeasured somatic constituents. The capacity to extend our models to 4 or more components is now at hand. Not only will this allow us to vastly expand our validation of two 2-compartment approaches, but our ability to explore new and important physiological questions is within reach.
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