Inhibitor of Growth 4 Induces Growth Suppression and Apoptosis in Glioma U87MG | Zendy

Xiaomei Li | Zendy; Limin Cai | Zendy; Hui Chen | Zendy; Qingyuan Zhang | Zendy; Shujun Zhang | Zendy; Yanhua Wang | Zendy; Yanyan Dong | Zendy; Hui Cheng | Zendy; Jiping Qi | Zendy

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Inhibitor of Growth 4 Induces Growth Suppression and Apoptosis in Glioma U87MG

Author(s) -

Xiaomei Li,

Limin Cai,

Hui Chen,

Qingyuan Zhang,

Shujun Zhang,

Yanhua Wang,

Yanyan Dong,

Hui Cheng,

Jiping Qi

Publication year - 2009

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000218334

Subject(s) - apoptosis , glioma , cell cycle , carcinogenesis , cell growth , biology , growth inhibition , western blot , cancer research , tunel assay , microbiology and biotechnology , signal transduction , chemistry , gene , biochemistry

Inhibitor of growth (ING) 4 is a member of the ING family proteins. It has been shown to play an important role in cell cycle, transcription and oncogenesis, but the molecular mechanism of ING4 on tumor growth inhibition has not yet been elucidated. The goal of this study is to investigate the inhibitory effects of ING4 on gliomas and its mechanism by transduction of ING4 cDNA into glioma U87MG.

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