MiR-125b Expression Affects the Proliferation and Apoptosis of Human Glioma Cells by Targeting Bmf | Zendy

Hong-Fei Xia | Zendy; Tian-Zhu He | Zendy; Chunmei Liu | Zendy; Yi Cui | Zendy; Peipei Song | Zendy; Xiaohua Jin | Zendy; Xu Ma | Zendy

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<i>MiR-125b</i> Expression Affects the Proliferation and Apoptosis of Human Glioma Cells by Targeting <i>Bmf</i>

Author(s) -

Hong-Fei Xia,

Tian-Zhu He,

Chunmei Liu,

Yi Cui,

Peipei Song,

Xiaohua Jin,

Xu Ma

Publication year - 2009

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000218181

Subject(s) - glioma , microrna , apoptosis , cell growth , biology , flow cytometry , cell culture , cancer research , microbiology and biotechnology , transfection , viability assay , retinoic acid , chemistry , gene , biochemistry , genetics

MicroRNAs (miRNAs) are small noncoding RNAs whose function as modulators of gene expression is crucial for the proper control of cell growth. Although many microRNAs were found to express in central nervous system (CNS), the role of the regulatory networks in which they are involved and their function in the pathological process of nerve cells are only just emerging. In the present study, the possible mechanisms by which one neuronal miRNAs, miR-125b, affected the growth of nervous cells were investigated using in vitro cell line model.

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