N-4-Tert-Butyl Benzyl Haloperidol Chloride Suppresses Ca2&plus;-dependent Egr-1 Expression and Subsequently Inhibits Vascular Smooth Muscle Cell Proliferation Induced by Angiotensin II | Zendy

Yicun Chen | Zendy; Jinhong Zheng | Zendy; Yanmei Zhang | Zendy; Jinzhi Wang | Zendy; Qing Liu | Zendy; Zhanqin Huang | Zendy; Fenfei Gao | Zendy; Yanqiong Zhou | Zendy; Ganggang Shi | Zendy

Open Access

<i>N</i>-4-Tert-Butyl Benzyl Haloperidol Chloride Suppresses Ca<sup>2+</sup>-dependent Egr-1 Expression and Subsequently Inhibits Vascular Smooth Muscle Cell Proliferation Induced by Angiotensin II

Author(s) -

Yicun Chen,

Jinhong Zheng,

Yanmei Zhang,

Jinzhi Wang,

Qing Liu,

Zhanqin Huang,

Fenfei Gao,

Yanqiong Zhou,

Ganggang Shi

Publication year - 2009

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000218176

Subject(s) - vascular smooth muscle , cell growth , chemistry , extracellular , western blot , microbiology and biotechnology , cyclin d1 , apoptosis , medicine , endocrinology , cell cycle , biology , biochemistry , smooth muscle , gene

N-4-Tert-Butyl benzyl haloperidol chloride (C(3)) was a novel calcium antagonist synthesized in our laboratory. The present study is to explore the effect of C(3) on vascular smooth muscle cell proliferation and the mechanism involved.

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