Mizoribine Suppresses the Progression of Experimental Peritoneal Fibrosis in a Rat Model
Author(s) -
Shunsuke Takahashi,
Yoshihiko Taniguchi,
Ayumu Nakashima,
Tetsuji Arakawa,
Tōru Kawai,
Shigehiro Doi,
Takafumi Ito,
Takao Masaki,
Nobuoki Kohno,
Noriaki Yorioka
Publication year - 2009
Publication title -
nephron experimental nephrology
Language(s) - English
Resource type - Journals
ISSN - 1660-2129
DOI - 10.1159/000213896
Subject(s) - mizoribine , peritoneal dialysis , fibrosis , medicine , cd163 , infiltration (hvac) , saline , peritoneum , pharmacology , pathology , chemistry , macrophage , physics , biochemistry , in vitro , thermodynamics
Peritoneal fibrosis is a serious complication of peritoneal dialysis (PD). It has been reported that administration of mizoribine, an effective immunosuppressant, ameliorated renal fibrosis in a rat model of unilateral ureteral obstruction. We therefore examined the effects of mizoribine in an experimental model of peritoneal fibrosis.
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