Uric Acid and Dementia in Community-Dwelling Older Persons | Zendy

Carmelinda Ruggiero | Zendy; Antonio Cherubini | Zendy; Fulvio Lauretani | Zendy; Stefania Bandinelli | Zendy; Marcello Maggio | Zendy; Angelo Di Iorio | Zendy; Giovanni Zuliani | Zendy; Charalampos Dragonas | Zendy; Umberto Senin | Zendy; Luigi Ferrucci | Zendy

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Uric Acid and Dementia in Community-Dwelling Older Persons

Author(s) -

Carmelinda Ruggiero,

Antonio Cherubini,

Fulvio Lauretani,

Stefania Bandinelli,

Marcello Maggio,

Angelo Di Iorio,

Giovanni Zuliani,

Charalampos Dragonas,

Umberto Senin,

Luigi Ferrucci

Publication year - 2009

Publication title -

dementia and geriatric cognitive disorders

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.026

H-Index - 110

eISSN - 1421-9824

pISSN - 1420-8008

DOI - 10.1159/000210040

Subject(s) - dementia , confounding , medicine , logistic regression , epidemiology , gerontology , uric acid , hyperuricemia , population , neuropsychology , disease , psychiatry , cognition , environmental health

The biological action of uric acid (UA) in humans is controversial. UA is considered an antioxidant compound, but preclinical evidence suggests a proinflammatory action. Epidemiological studies found that hyperuricemia is associated with conditions leading to dementia. Our aim is to investigate the relationship between UA levels and dementia in older persons.

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