Hodgkin’s Disease and Pregnancy

This is a short communication in which 2 cases of familiar Hodgkin's disease are reported. The first case is a 27 years old woman with the diagnosis of Hodgkin's disease, nodular sclerosis, stage III-B (with mediastinal, para-aortic and right supraclavicular involvement), treated initially with radical radiotherapy. She was pregnant at the time of diagnosis. The second case is a 15 years old woman with similar diagnosis of Hodgkin's disease stage II-A (with mediastinal and right supraclavicular involvement) and identical histology. She was the daughter of case 1. The observation of familiar Hodgkin's disease and its possible biological implications are discussed.