No Genetic Association between Polymorphisms of Heme Oxygenase 1 and 2 and Alzheimer’s Disease in a Japanese Population
Author(s) -
Nobuto Shibata,
Tohru Ohnuma,
Hajime Baba,
Heii Arai
Publication year - 2009
Publication title -
dementia and geriatric cognitive disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.026
H-Index - 110
eISSN - 1421-9824
pISSN - 1420-8008
DOI - 10.1159/000203891
Subject(s) - hmox1 , single nucleotide polymorphism , genetic association , apolipoprotein e , genetics , alzheimer's disease , biology , disease , pathogenesis , heme oxygenase , genotype , gene , genome wide association study , psen1 , taqman , allele , bioinformatics , medicine , heme , presenilin , pathology , immunology , polymerase chain reaction , biochemistry , enzyme
Recently, it has been shown that the heme oxygenases HMOX1 and HMOX2 might play a role in the pathogenesis of Alzheimer's disease (AD).
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