Open AccessImmune Ontogeny and Engraftment Receptivity in the Sheep Fetus
Author(s) -
Jessica L. Skopal-Chase,
John S. Pixley,
Alireza Torabi,
Mihai Cenariu,
Anupama Bhat,
David Thain,
Nicole M. Frederick,
Daria Groza,
Esmail D. Zanjani
Publication year - 2009
Publication title -
fetal diagnosis and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.976
H-Index - 60
eISSN - 1421-9964
pISSN - 1015-3837
DOI - 10.1159/000203399
Subject(s) - fetus , transplantation , immune system , gestation , andrology , cd8 , biology , t cell , immunology , medicine , pregnancy , genetics
The biologic explanation for fetal receptivity to donor engraftment and subsequent long-term tolerance following transplantation early in gestation is not known. We investigated the role fetal immune ontogeny might play in fetal transplantation tolerance in sheep.
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