English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The majority of melanocytic nevi on the soles may show 3 major dermoscopic patterns depending on the anatomical site on the sole [6] : the parallel furrow, the lattice-like, and the fibrillar patterns. Regular or irregular patterns should be identified in the fibrillar pattern. The regular fibrillar pattern is seen in acral volar melanocytic nevus, whereas the irregular fibrillar pattern is often seen partly or entirely in acral lentiginous melanoma of the pressure-loaded area of the sole. However, the difference between regular and irregular fibrillar patterns has not yet clearly been defined, although it is very important to distinguish these differences to discriminate an early acral melanoma from an acquired acral melanocytic nevus. The regular fibrillar pattern can be regarded as an artifactual expression  of the parallel furrow pattern [5, 6] . We have proved that the fibrillar pattern is directly caused by an oblique arrangement of melanin pigment columns in the slanting stratum corneum with a three-dimensional reconstruction method using specimens of acral nevi of parallel furrow or fibrillar patterns [7] . The slanting of the stratum corneum is considered to be produced by mechanical pressure from the body weight. Miyazaki et al. [6] already reported that the regular fibrillar pattern of an acral nevus was changed to the parallel furrow pattern by horizontally moving the stratum corneum with the probe of a dermoscope. Therefore, oblique view dermoscopy at a angle to the stratum corneum could change the regular fibrillar pattern into a parallel furrow pattern. A 37-year-old Japanese female presented with a dark brown macule on the lateral side of the left sole (body-weight-loaded area). She had been aware of the lesion for several years. Dermoscopy examination revealed a typical regular fibrillar pattern, and a diagnosis of acquired melanocytic nevus was made. The slanting angle of the melanin columns in the stratum corneum was confirmed by use of DermLite DL-100 (3Gen, Dana Point, Calif., USA). After the direction of viewing was fixed so that the parallel furrow pattern was observed, pictures were taken with the Der

Oblique View Dermoscopy Changes Regular Fibrillar Pattern into Parallel Furrow Pattern