Variance Components Linkage Analysis with Repeated Measurements | Zendy

Liming Liang | Zendy; WeiMin Chen | Zendy; Pak C. Sham | Zendy; Gonçalo R. Abecasis | Zendy

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Variance Components Linkage Analysis with Repeated Measurements

Author(s) -

Liming Liang,

WeiMin Chen,

Pak C. Sham,

Gonçalo R. Abecasis

Publication year - 2008

Publication title -

human heredity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.423

H-Index - 62

eISSN - 1423-0062

pISSN - 0001-5652

DOI - 10.1159/000194977

Subject(s) - heritability , linkage (software) , statistics , repeated measures design , mathematics , trait , variance (accounting) , statistical power , econometrics , computer science , genetics , biology , accounting , business , gene , programming language

When subjects are measured multiple times, linkage analysis needs to appropriately model these repeated measures. A number of methods have been proposed to model repeated measures in linkage analysis. Here, we focus on assessing the impact of repeated measures on the power and cost of a linkage study.

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