The Role of Angiogenic Growth Factors in Arteriogenesis | Zendy

Wilma Schierling | Zendy; Kerstin Troidl | Zendy; Christian Troidl | Zendy; Thomas SchmitzRixen | Zendy; Wolfgang Schäper | Zendy; Inka Eitenmüller | Zendy

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The Role of Angiogenic Growth Factors in Arteriogenesis

Author(s) -

Wilma Schierling,

Kerstin Troidl,

Christian Troidl,

Thomas SchmitzRixen,

Wolfgang Schäper,

Inka Eitenmüller

Publication year - 2009

Publication title -

journal of vascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.58

H-Index - 74

eISSN - 1423-0135

pISSN - 1018-1172

DOI - 10.1159/000189797

Subject(s) - arteriogenesis , angiogenesis , medicine , growth factor , receptor , femoral artery , endocrinology

Collateral vessels restore only about 40% of the maximum dilatory reserve after femoral artery occlusion, whereas complete normalization is reached by increased fluid shear stress (FSS). We studied the role of known potent angiogenic growth factors (separately or in combination) in arteriogenesis by determining their expression in FSS-stimulated collaterals and close-to-collateral infusion of growth factor peptides in a rabbit model of femoral artery occlusion.

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