Age at Renal Replacement Therapy in Autosomal Dominant Polycystic Kidney Disease

Ana Gonzalo, MD, Servicio de Nefrologia, Hospital Ramon y Cajal, Carretera de Colmenar Km 9,100, E-28034 Madrid (Spain) Dear Sir, In 1989 Gretz et al. [1] pointed out that end-stage renal failure appears earlier in men than in women in autosomal dominant polycystic kidney disease (ADPKD; median age 52 vs. 58 years). Data from the Australia and New Zealand Dialysis and Transplant Registry [2] and recently those from Gabow and Johnson [3] in ADPKDl patients supported Table 1. Age and sex distribution at the start of renal replacement therapy in 82 ADPKD patients