Common Variants in Interleukin-1-Beta Gene Are Associated with Intracranial Hemorrhage and Susceptibility to Brain Arteriovenous Malformation | Zendy

Helen Kim | Zendy; Pirro G. Hysi | Zendy; Ludmila Pawlikowska | Zendy; Annie Poon | Zendy; Esteban G. Burchard | Zendy; Jonathan G. Zaroff | Zendy; Stephen Sidney | Zendy; Nerissa Ko | Zendy; Achal S. Achrol | Zendy; Michael T. Lawton | Zendy; Charles E. McCulloch | Zendy; PuiYan Kwok | Zendy; William L. Young | Zendy

Open Access

Common Variants in Interleukin-1-Beta Gene Are Associated with Intracranial Hemorrhage and Susceptibility to Brain Arteriovenous Malformation

Author(s) -

Helen Kim,

Pirro G. Hysi,

Ludmila Pawlikowska,

Annie Poon,

Esteban G. Burchard,

Jonathan G. Zaroff,

Stephen Sidney,

Nerissa Ko,

Achal S. Achrol,

Michael T. Lawton,

Charles E. McCulloch,

PuiYan Kwok,

William L. Young

Publication year - 2008

Publication title -

cerebrovascular diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.221

H-Index - 104

eISSN - 1421-9786

pISSN - 1015-9770

DOI - 10.1159/000185609

Subject(s) - medicine , single nucleotide polymorphism , genotype , intracerebral hemorrhage , gastroenterology , snp , hazard ratio , arteriovenous malformation , gene , surgery , subarachnoid hemorrhage , genetics , confidence interval , biology

Polymorphisms in the proinflammatory cytokine interleukin (IL)-1beta gene have been associated with systemic atherogenesis, thrombosis and rupture. The aim of this study was to investigate associations between single nucleotide polymorphisms (SNPs) in IL-1beta and intracranial hemorrhage (ICH) in the natural course of brain arteriovenous malformation (BAVM) patients.

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