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Dr. Shunichi Kojima, Department of Medicine, National Cardiovascular Center Hospital, Fujishirodai 5-7-1, Suita, Osaka 565 (Japan) Dear Sir, We have been studying the changes in plasma levels of atrial natriuretic peptide (ANP) and its physiological effects during supraventricular tachycardia (STV) [1, 2]. The main stimulus for ANP release was confirmed to be an atrial distension and/or an increase of atrial pressure [3]. Although Marumo et al. [4] demonstrated the presence of ANP in urine, there have been few studies about the changes in urinary excretion of ANP during stimulation of ANP release. The aim of this study was to compare plasma levels and urinary excretion of ANP during saline infusion and SVT. saline infusion (1500ml) saline infusion(1500mli

Urinary Excretion of Atrial Natriuretic Peptide during Saline Infusion and Supraventricular Tachycardia