Open AccessDeviations from Hardy-Weinberg Equilibrium in Parental and Unaffected Sibling Genotype Data
Author(s) -
Bingshan Li,
Suzanne M. Leal
Publication year - 2008
Publication title -
human heredity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 62
eISSN - 1423-0062
pISSN - 0001-5652
DOI - 10.1159/000179558
Subject(s) - genotype , sibling , hardy–weinberg principle , genetics , biology , genotyping , locus (genetics) , proband , genotype frequency , allele , allele frequency , psychology , mutation , gene , developmental psychology
Genotyping error can increase both type I and II errors. In order to elucidate potential genotyping errors, data quality control often includes testing genotype data for deviations from Hardy-Weinberg Equilibrium (HWE).
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