COX-2 Expression Does Not Correlate with Microvessel Density in Breast Cancer | Zendy

Mangesh A. Thorat | Zendy; Sanjana Mehrotra | Zendy; Akira Morimiya | Zendy; Sunil Badve | Zendy

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COX-2 Expression Does Not Correlate with Microvessel Density in Breast Cancer

Author(s) -

Mangesh A. Thorat,

Sanjana Mehrotra,

Akira Morimiya,

Sunil Badve

Publication year - 2009

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000178154

Subject(s) - breast cancer , microvessel , medicine , oncology , expression (computer science) , cancer , cancer research , pathology , biology , angiogenesis , computer science , programming language

Cyclooxygenase-2 (COX-2), implicated in carcinogenesis and tumour progression in many cancers including breast cancer, is hypothesised to cause progression by promoting angiogenesis. The exact mechanism of such action is not known and the clinical evidence of such interaction is weak. We studied COX-2 expression and microvessel density (MVD) in malignant breast tissues.

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