Chemotherapy in Patients with Penile Carcinoma | Zendy

Chris Protzel | Zendy; Oliver W. Hakenberg | Zendy

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Chemotherapy in Patients with Penile Carcinoma

Author(s) -

Chris Protzel,

Oliver W. Hakenberg

Publication year - 2009

Publication title -

urologia internationalis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.771

H-Index - 53

eISSN - 1423-0399

pISSN - 0042-1138

DOI - 10.1159/000176016

Subject(s) - medicine , taxane , penile cancer , chemotherapy , oncology , lymph node , adjuvant , carcinoma , penile carcinoma , cancer , urology , breast cancer

The prognosis of patients with advanced penile carcinoma is poor. There are only few studies, mostly with a low number of patients, which show a low response rate with severe toxicity. While adjuvant and palliative chemotherapy for penile cancer is universally characterized by low efficacy, neoadjuvant approaches for patients with fixed lymph node metastases have shown some response. Overall, recent experiences with new chemotherapeutic approaches (i.e. taxane-based combinations) have shown some encouraging results. Therefore, these combinations should be investigated in larger and multi-center studies.

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