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H-Dmt-D-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA), a highly selective micro-opioid peptide, is potently analgesic after systemic and intrathecal administration but is less potent given intracerebroventricularly. This study was performed to further characterize the analgesic effects of [Dmt(1)]DALDA.

Differential Analgesic Effects of a Mu-Opioid Peptide, [Dmt<sup>1</sup>]DALDA, and Morphine