Susceptibility of <i>XRCC3, XPD, </i>and <i>XPG</i> Genetic Variants to Cervical Carcinoma
Author(s) -
Xiaohong He,
Feng Ye,
Jing Zhang,
Qi Cheng,
Jiajie Shen,
Huaizeng Chen
Publication year - 2008
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000164220
Subject(s) - xrcc3 , xeroderma pigmentosum , single nucleotide polymorphism , biology , cancer research , carcinogenesis , nucleotide excision repair , cervical intraepithelial neoplasia , dna polymerase , genotype , dna repair , genetics , cervical cancer , microbiology and biotechnology , gene , cancer
DNA repair genes play a key role in maintaining genomic stability and integrity. DNA repair gene polymorphisms, such as those of XRCC3 and xeroderma pigmentosum, complementation group D and G (XPD, XPG), contribute to carcinogenesis. In this study, we investigated the correlation between cervical carcinoma risk and XRCC3, XPD, XPG genetic variants.
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