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Specific Induction of Tumor Neovasculature Death by Modified Murine PPE-1 Promoter Armed with HSV-TK
Author(s) -
Nira VardaBloom,
Israel Hodish,
Aviv Shaish,
Shoshana Greenberger,
Reshef Tal,
Bela Feder,
Joseph Roitelman,
Eyal Breitbart,
Livnat Bangio,
Iris Barshack,
Raphael Pfeffer,
Dror Harats
Publication year - 2008
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000164219
Subject(s) - cancer research , angiogenesis , lewis lung carcinoma , promoter , microbiology and biotechnology , in vivo , metastasis , reporter gene , genetic enhancement , biology , thymidine kinase , viral vector , herpes simplex virus , gene expression , immunology , gene , cancer , virus , recombinant dna , biochemistry , genetics
One strategy to increase tissue specificity of gene therapy is to use promoters or enhancers.

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