In vivo Efficacy of Marimastat and Chemoradiation in Head and Neck Cancer Xenografts
Author(s) -
Joni B. Skipper,
Lacey R. McNally,
Eben L. Rosenthal,
Wenquan Wang,
Donald J. Buchsbaum
Publication year - 2008
Publication title -
orl
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.481
H-Index - 44
eISSN - 1423-0275
pISSN - 0301-1569
DOI - 10.1159/000163217
Subject(s) - cisplatin , medicine , radiation therapy , head and neck cancer , in vivo , doubling time , head and neck squamous cell carcinoma , matrix metalloproteinase , chemotherapy , urology , cell , chemistry , biology , biochemistry , microbiology and biotechnology
To assess the effect of combining a synthetic matrix metalloprotease inhibitor and chemoradiation therapy on tumor growth in a murine model of head and neck squamous-cell carcinoma (SCC).
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