Open AccessImpact of Nasal Continuous Positive Airway Pressure Therapy on Markers of Platelet Activation in Patients with Obstructive Sleep Apnea
Author(s) -
Morohunfolu E. Akinnusi,
Linda L. Paasch,
Kristie R. Szarpa,
Paul K. Wallace,
Ali A. El Solh
Publication year - 2008
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000158488
Subject(s) - medicine , continuous positive airway pressure , obstructive sleep apnea , platelet activation , platelet , monocyte , endocrinology , immunology
Considerable evidence implicates CD40 signaling in the pathogenesis of atheromas. Exposure to CD40 ligand induces platelet-leukocyte conjugation, a heightened expression of inflammatory cytokines, matrix-degrading enzymes, and procoagulant factors.
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