Cell Therapy for Age-Related Disorders: Myocardial Infarction and Stroke – A Mini-Review | Zendy

Brent A. Williams | Zendy; Armand Keating | Zendy

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Cell Therapy for Age-Related Disorders: Myocardial Infarction and Stroke – A Mini-Review

Author(s) -

Brent A. Williams,

Armand Keating

Publication year - 2008

Publication title -

gerontology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.397

H-Index - 94

eISSN - 1423-0003

pISSN - 0304-324X

DOI - 10.1159/000156223

Subject(s) - medicine , myocardial infarction , stroke (engine) , clinical trial , cardiology , stem cell therapy , transplantation , cell therapy , stem cell , percutaneous coronary intervention , ejection fraction , infarction , heart failure , progenitor cell , mechanical engineering , biology , engineering , genetics

The leading causes of death and disability in the elderly are from cardiovascular and cerebrovascular diseases. The biological role of stem cells in the hematopoietic system has been well characterized and has led to the development of hematopoietic stem and progenitor cell (HSPC) transplantation for the treatment of numerous malignant and nonmalignant diseases. More recently, stem cells have been found in many other tissues of the body including the heart and brain. As the field of stem cell biology has progressed, cell therapies for the treatment of myocardial infarction and stroke have been tested in early stage clinical trials using a variety of cellular agents.

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