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Histopathological Correlates of the Parallel-Furrow Pattern Seen in Acral Melanocytic Naevi at Dermatoscopy
Author(s) -
Giovanni Maria Palleschi,
Carmelo Urso,
Eugenio Torre,
Daniele Torchia
Publication year - 2008
Publication title -
dermatology
Language(s) - English
Resource type - Journals
eISSN - 1421-9832
pISSN - 1018-8665
DOI - 10.1159/000156085
Subject(s) - dermatoscopy , dermatology , melanocytic nevus , medicine , nevus , pathology , melanoma , cancer research
compound melanocytic naevus was made. The remaining portion of the lesion was used for transverse histological sectioning to reproduce the original dermatoscopic plan, as tissue sections were parallel to the skin surface ( fig. 2 b). The analysis of transverse sections showed several pigmented structures: types of melanin in the horny layer under the ridges, junctional and papillary nests of melanocytes, as well as melanocyte cords in the subpapillary dermis ( fig. 2 c–h). Junctional nests were present in both cristae limitantes and cristae intermediae. This finding, that was also presented in the paper by Kimoto et al. [1] , is quite surprising. In fact, it is commonly stated that the histopathological correlates of the PFP and parallel-ridge pattern (i.e. the dermatoscopic hallmark of acral melanoma) are a proliferation of pigmented cells within the cristae limitantes or the cris

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