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Polymorphisms of Homocysteine Metabolism Are Associated with Intracranial Aneurysms
Author(s) -
Alexander Semmler,
Michael Linnebank,
Dietmar Krex,
Anika Götz,
Susanna Moskau,
Andreas Ziegler,
Matthias Simon
Publication year - 2008
Publication title -
cerebrovascular diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.221
H-Index - 104
eISSN - 1421-9786
pISSN - 1015-9770
DOI - 10.1159/000155638
Subject(s) - methylenetetrahydrofolate reductase , homocysteine , medicine , odds ratio , cystathionine beta synthase , gastroenterology , methionine synthase , mtrr , hyperhomocysteinemia , allele , reductase , endocrinology , genetics , methionine , biology , biochemistry , enzyme , gene , amino acid
Impaired homocysteine metabolism is associated with a number of vasculopathies including extracranial aneurysms. We analyzed the possible association of nine genetic variants of homocysteine metabolism with the occurrence of intracranial aneurysms.

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