Open AccessInhibition of the Magnesium-Sensitive TRPM7-like Channel in Cardiac Myocytes by Nonhydrolysable GTP Analogs: Involvement of Phosphoinositide Metabolism
Author(s) -
Regina Mačianskienė,
Asfree Gwanyanya,
Johan Vereecke,
Kanigula Mubagwa
Publication year - 2008
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000149788
Subject(s) - gtp' , trpm7 , intracellular , chemistry , myocyte , microbiology and biotechnology , g protein , biophysics , biology , biochemistry , ion channel , signal transduction , receptor , enzyme
A magnesium-inhibited, transient receptor potential melastatin 7 (TRPM7)-like channel is expressed in cardiac cell membranes. The role and regulation of this channel by intracellular nucleotides and membrane components remain unclear.
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