Modes of Action of the New Arylguanidine Abafungin beyond Interference with Ergosterol Biosynthesis and in vitro Activity against Medically Important Fungi | Zendy

Claudia Borelli | Zendy; Martin Schaller | Zendy; M. Niewerth | Zendy; K. Nocker | Zendy; B. Baasner | Zendy; Deborah Berg | Zendy; Ralf Tiemann | Zendy; Klaus Tietjen | Zendy; Burkhard Fugmann | Zendy; Susanne LangFugmann | Zendy; H.C. Korting | Zendy

Open Access

Modes of Action of the New Arylguanidine Abafungin beyond Interference with Ergosterol Biosynthesis and in vitro Activity against Medically Important Fungi

Author(s) -

Claudia Borelli,

Martin Schaller,

M. Niewerth,

K. Nocker,

B. Baasner,

Deborah Berg,

Ralf Tiemann,

Klaus Tietjen,

Burkhard Fugmann,

Susanne LangFugmann,

H.C. Korting

Publication year - 2008

Publication title -

chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.539

H-Index - 54

eISSN - 1421-9794

pISSN - 0009-3157

DOI - 10.1159/000142334

Subject(s) - mode of action , ergosterol , sterol , antifungal , biology , in vitro , pharmacology , mechanism of action , microbiology and biotechnology , biological activity , biochemistry , chemistry , cholesterol

In contrast to the increasing numbers of agents for the treatment of invasive fungal infections, discoveries of new antifungal agents with therapeutic value in dermatomycoses are reported only rarely.

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