Open AccessNorepinephrine and E139 Interactions on Epileptiform Activity in the Rat Hippocampus in vitro
Author(s) -
Samuel B. Kombian,
Kethireddy V.V. Ananthalakshmi,
Ivan O. Edafiogho
Publication year - 2008
Publication title -
medical principles and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 45
eISSN - 1423-0151
pISSN - 1011-7571
DOI - 10.1159/000141499
Subject(s) - yohimbine , prazosin , population spike , hippocampal formation , population , phentolamine , norepinephrine , medicine , endocrinology , antagonist , hippocampus , pharmacology , propranolol , receptor , dopamine , dentate gyrus , environmental health
We tested if E139, an anticonvulsant enaminone, interacts with norepinephrine (NE) to suppress population responses and chemically induced in vitro seizures in the rat hippocampus.
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