Genotype-Phenotype Associations in Obesity Dependent on Definition of the Obesity Phenotype | Zendy

Sofia I. Iqbal Kring | Zendy; Lesli H. Larsen | Zendy; Claus Holst | Zendy; S Toubro | Zendy; Torben Hansen | Zendy; Arne Astrup | Zendy; Oluf Pedersen | Zendy; Thorkild I.A. S oslash rensen | Zendy

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Genotype-Phenotype Associations in Obesity Dependent on Definition of the Obesity Phenotype

Author(s) -

Sofia I. Iqbal Kring,

Lesli H. Larsen,

Claus Holst,

S Toubro,

Torben Hansen,

Arne Astrup,

Oluf Pedersen,

Thorkild I.A. S oslash rensen

Publication year - 2008

Publication title -

obesity facts

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.398

H-Index - 45

eISSN - 1662-4033

pISSN - 1662-4025

DOI - 10.1159/000137665

Subject(s) - medicine , waist , minor allele frequency , body mass index , obesity , abdominal obesity , anthropometry , genotype , endocrinology , allele frequency , genetics , biology , gene

In previous studies of associations of variants in the genes UCP2, UCP3, PPARG2, CART, GRL, MC4R, MKKS, SHP, GHRL, and MCHR1 with obesity, we have used a case-control approach with cases defined by a threshold for BMI. In the present study, we assess the association of seven abdominal, peripheral, and overall obesity phenotypes, which were analyzed quantitatively, and thirteen candidate gene polymorphisms in these ten genes in the same cohort.

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