Open AccessMarkedly Different Clinical Features in 2 Diabetes Mellitus Patients with Extremely High Tissue Levels of the Mitochondrial DNA A3243G Mutation
Author(s) -
Shinji Harihara,
Kenichi Nakamura,
Mutsunori Fujiwara,
Tomio Arai,
Motoji Sawabe,
Fujio Takeuchi,
Kaiyo Takubo
Publication year - 2008
Publication title -
gerontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.397
H-Index - 94
eISSN - 1423-0003
pISSN - 0304-324X
DOI - 10.1159/000127415
Subject(s) - mitochondrial dna , diabetes mellitus , mutation , medicine , endocrinology , mitochondrion , dna , genetics , biology , gene
Mitochondrial DNA (mtDNA) A3243G mutation is one of the major causative factors of mitochondrial diabetes mellitus. We found that tissues from 2 of 142 diabetes mellitus patients showed extremely high levels of the mutation.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom