Open AccessMicrobial Products Trigger Autoimmune Ocular Inflammation
Author(s) -
Chiaki Fujimoto,
Guangpu Shi,
Igal Gery
Publication year - 2008
Publication title -
ophthalmic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 54
eISSN - 1423-0259
pISSN - 0030-3747
DOI - 10.1159/000119875
Subject(s) - inflammation , immune system , effector , autoimmunity , immunology , biology , receptor , t cell , microbiology and biotechnology , biochemistry
Microbial products stimulate the immune system by interacting with Toll-like receptors (TLR) on antigen-presenting cells. This study examined the hypothesis that microbial products, which function as TLR ligands, are playing a major role in triggering pathogenic autoimmunity.
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