Whole Blood Assays to Identify Th1 Cell Antigens and Peptides Encoded by <i>Mycobacterium tuberculosis</i>-Specific RD1 Genes
Author(s) -
Shumaila Nida Muhammad Hanif,
Abdulsalam M. El-Shammy,
Rajaa AlAttiyah,
Abu Salim Mustafa
Publication year - 2008
Publication title -
medical principles and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 45
eISSN - 1423-0151
pISSN - 1011-7571
DOI - 10.1159/000117800
Subject(s) - antigen , mycobacterium bovis , mycobacterium tuberculosis , tuberculosis , orfs , mycobacterium , interferon gamma , mycobacterium tuberculosis complex , biology , immunology , medicine , microbiology and biotechnology , gene , open reading frame , immune system , peptide sequence , biochemistry , pathology
To identify Th1 cell-stimulating antigens/peptides encoded by the genes predicted in the Mycobacterium tuberculosis-specific genomic region of difference (RD)1, deleted in Mycobacterium bovis Bacille Calmette-Guérin(BCG), by using synthetic peptides and whole blood from tuberculosis (TB) patients.
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