Role of Biologics and Other Therapies in Stricturing Crohn’s Disease: What Have We Learnt So Far?

Therapy of strictures, one of the most common complications of Crohn's disease (CD), remains a challenging task in gastroenterology. While infliximab is widely recognized as being very effective in active CD, it has been reported to cause strictures in some patients. As a consequence, essentially by inference, many clinicians have chosen not to use it in the presence of strictures.