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Reduced Expression and Function of Aquaporin-3 in Mouse Metaphase-II Oocytes Induced by Controlled Ovarian Hyperstimulation were Associated with Subsequent Low Fertilization Rate
Author(s) -
Qingxia Meng,
Huijuan Gao,
Chenming Xu,
Minyue Dong,
Xia Sheng,
JianZhong Sheng,
HeFeng Huang
Publication year - 2008
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000113754
Subject(s) - controlled ovarian hyperstimulation , andrology , human fertilization , aquaporin , aquaporin 2 , metaphase , function (biology) , endocrinology , in vitro fertilisation , biology , oocyte , medicine , microbiology and biotechnology , chemistry , embryo , water channel , anatomy , genetics , gene , chromosome , mechanical engineering , engineering , inlet
Aquaporin-3 (AQP3), one isoform of water channel family, has been found to be expressed in mouse oocytes. The present study aimed to investigate whether functional AQP3 was expressed in oocytes induced by controlled ovarian hyperstimulation (COH), and whether altered oocyte AQP3 expression was associated with changes in fertilization rate.

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