Direct Comparison of Human Mesenchymal Stem Cells Derived from Adipose Tissues and Bone Marrow in Mediating Neovascularization in Response to Vascular Ischemia
Author(s) -
Yeon Jeong Kim,
Hoe Kyu Kim,
Hyun Hwa Cho,
Yong Chan Bae,
Kuen Tak Suh,
Jin Sup Jung
Publication year - 2007
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000110447
Subject(s) - transplantation , mesenchymal stem cell , adipose tissue , medicine , stem cell , angiogenesis , neovascularization , pathology , biology , microbiology and biotechnology
Although transplantation of MSC derived from bone marrow or adipose tissues has been shown in proangiogenic action in hindlimb ischemia model of nude mice, little information is available regarding comparison of the angiogenic potency between human adipose stromal cells (hADSC) and bone marrow stromal cells (hBMSC). We compared their therapeutic potential by transplantation of equal numbers of hADSC or hBMSC in a nude mice model of hindlimb ischemia.
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