Male and Female Breast Cancer – Differences in DNA Ploidy, p21 and p53 Expression Reinforce the Possibility of Distinct Pathways of Oncogenesis | Zendy

Saudade André | Zendy; António E. Pinto | Zendy; Cátia Laranjeira | Zendy; Manuela Quaresma | Zendy; Jorge Soares | Zendy

Open Access

Male and Female Breast Cancer – Differences in DNA Ploidy, p21 and p53 Expression Reinforce the Possibility of Distinct Pathways of Oncogenesis

Author(s) -

Saudade André,

António E. Pinto,

Cátia Laranjeira,

Manuela Quaresma,

Jorge Soares

Publication year - 2007

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000110025

Subject(s) - carcinogenesis , biology , cell cycle , immunohistochemistry , ploidy , grading (engineering) , aneuploidy , cancer , ki 67 , breast cancer , flow cytometry , cancer research , pathology , microbiology and biotechnology , genetics , gene , medicine , chromosome , immunology , ecology

The purpose of this study was to compare the immunohistochemical profile of cell cycle inhibitors of G1/S phase transition (p21, p53 and pRb), Ki-67 proliferation marker and DNA ploidy in male (MBC) and female breast cancer (FBC).

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