The Heritability of Abstract Reasoning in Caribbean Latinos with Familial Alzheimer Disease
Author(s) -
Beverly Johnson,
Vincent Santana,
Nicole Schupf,
Ming-X Tang,
Yaakov Stern,
Richard Mayeux,
Joseph H. Lee
Publication year - 2007
Publication title -
dementia and geriatric cognitive disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.026
H-Index - 110
eISSN - 1421-9824
pISSN - 1420-8008
DOI - 10.1159/000109765
Subject(s) - heritability , apolipoprotein e , psychology , allele , wechsler adult intelligence scale , developmental psychology , genetics , disease , cognition , medicine , gene , biology , psychiatry
Alzheimer disease (AD) is under substantial genetic influence. To better understand the genetic influence on component phenotypes of AD, we estimated the heritability (h(2)) of abstract reasoning and examined its relation with apolipoprotein epsilon 4 (APOE-epsilon 4).
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