Cardiac Biomarkers in Haemodialysis Patients: The Prognostic Value of Amino-Terminal Pro-B-Type Natriuretic Peptide and Cardiac Troponin T | Zendy

Claudia Sommerer | Zendy; Evangelos Giannitsis | Zendy; Vedat Schwenger | Zendy; Martin Zeier | Zendy

Open Access

Cardiac Biomarkers in Haemodialysis Patients: The Prognostic Value of Amino-Terminal Pro-B-Type Natriuretic Peptide and Cardiac Troponin T

Author(s) -

Claudia Sommerer,

Evangelos Giannitsis,

Vedat Schwenger,

Martin Zeier

Publication year - 2007

Publication title -

nephron clinical practice

Language(s) - English

Resource type - Journals

ISSN - 1660-2110

DOI - 10.1159/000108647

Subject(s) - medicine , natriuretic peptide , cardiology , troponin t , amino terminal , nephrology , troponin , troponin i , hemodialysis , heart failure , myocardial infarction , peptide sequence , biochemistry , chemistry , gene

Cardiac biomarkers such as amino-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTNT) provide information on cardiovascular morbidity and mortality in patients with normal renal function. In a considerable number of chronic haemodialysis patients, both biomarkers - NT-proBNP and cTNT - are elevated despite the absence of cardiac ischaemia. The elevation of cardiac biomarkers in chronic haemodialysis patients is of prognostic value with respect to cardiovascular morbidity and mortality. They provide a useful rationale for the screening of occult cardiac disease and optimization of the dialysis procedure with respect to volume control.

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