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Growth Hormone Therapy for Short Children Born Small for Gestational Age
Author(s) -
Pierre Chatelain,
Antonio Carrascosa,
Gianni Bona,
Angel FerrandezLongás,
W.G. Sippell
Publication year - 2007
Publication title -
hormone research in paediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.816
H-Index - 89
eISSN - 1663-2826
pISSN - 1663-2818
DOI - 10.1159/000107935
Subject(s) - small for gestational age , short stature , medicine , growth hormone , growth hormone treatment , human growth hormone , endocrinology , gestational age , pediatrics , hormone , pregnancy , biology , genetics
Children born small for gestational age may demonstrate continued growth retardation, resulting in persistent short stature. In the majority of the cases, this is linked with abnormal growth hormone secretion and also abnormal insulin-like growth factor levels. This review discusses the treatment of such children with recombinant human growth hormone. It illustrates the importance of starting therapy early, the dose-dependent response, and the advantages of continuous therapy and describes safety considerations.

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