A Suppository Chinese Medicine (Xilei-san) for Refractory Ulcerative Proctitis: A Pilot Clinical Trial | Zendy

Ken Fukunaga | Zendy; Nobuyuki Hida | Zendy; Kunio Ohnishi | Zendy; Yoshio Ohda | Zendy; Koji Yoshida | Zendy; Takeshi Kusaka | Zendy; Yoshio Jinno | Zendy; Kazuko Nagase | Zendy; Shirô Nakamura | Zendy; Muneo Kadobayashi | Zendy; Hiroto Miwa | Zendy; Takayuki Matsumoto | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

A Suppository Chinese Medicine (Xilei-san) for Refractory Ulcerative Proctitis: A Pilot Clinical Trial

Author(s) -

Ken Fukunaga,

Nobuyuki Hida,

Kunio Ohnishi,

Yoshio Ohda,

Koji Yoshida,

Takeshi Kusaka,

Yoshio Jinno,

Kazuko Nagase,

Shirô Nakamura,

Muneo Kadobayashi,

Hiroto Miwa,

Takayuki Matsumoto

Publication year - 2007

Publication title -

digestion

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.882

H-Index - 75

eISSN - 1421-9867

pISSN - 0012-2823

DOI - 10.1159/000106755

Subject(s) - suppository , medicine , ulcerative colitis , refractory (planetary science) , proctitis , clinical trial , gastroenterology , pilot trial , traditional chinese medicine , randomized controlled trial , pathology , pharmacology , alternative medicine , disease , physics , astrobiology

posed as a possible indication of peroral XS. We have hypothesized that XS might be a useful therapeutic option for active UP patients refractory to conventional topical therapies if it would be applied in suppository form. A prospective open-labeled clinical trial was held from April 1, 2005 to December 31, 2006 to evaluate the efficacy of SXS for active refractory UP patients. Mean ( 8 SD) age and duration of UP of the enrolled patients were 36.2 8 9.1 years and 56.3 8 47.4 months, respectively. All patients had an episode of treatment with a combination of either peroral 5Dear Sir, Six patients with active ulcerative proctitis (UP) (male/female = 2/4) were treated with an originally developed suppository Xilei-san (SXS), a traditional Chinese medicine, which is composed of watermelon frost, calcite, cow gallstone, peal powder, borax, borneol, indigo, and ammonium chloride. This mixed traditional medicine has a long history in China and it has been accepted as a medicine for erosions and ulcerations of the tongue, pharynx and oral cavity. The therapeutic mechanism of XS has never been fully understood, but some domestic reports inform that ulcerative colitis (UC) has been proPublished online: August 3, 2007

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research