Spreading Dystonia in Probable Creutzfeldt-Jakob Disease with Serial Diffusion-Weighted Magnetic Resonance Images

turing of the left upper extremity. The dystonic posture of the left upper extremity caused levitation of the arm with flexed fingers and an extended wrist. Stimulussensitive generalized myoclonic jerks were Dear Sir, Creutzfeld-Jakob disease (CJD) is a progressive spongiform encephalopathy that is mainly characterized by rapidly progressive dementia, myoclonus, ataxia, epilepsia partialis continua, visual disturbances and movement disorders [1–7] . Several movement disorders including myoclonus, dystonia, choreoathetosis, tremor and parkinsonism have been described in a significant number of patients with CJD [8] . However, dystonia as an early symptom is rare. We report a patient who showed generalized dystonia followed by focal dystonia in early-stage disease with concomitant lesions on diffusionweighted MR images (DWI).