A Better Cure Rate with 800 mg than with 400 mg Clarithromycin Regimens in One-Week Triple Therapy for Helicobacter pylori Infection in Cigarette-Smoking Peptic Ulcer Patients | Zendy

Hidehiko Ishioka | Zendy; Motowo Mizuno | Zendy; Susumu Take | Zendy; Kuniharu Ishiki | Zendy; Yasuhiro Nagahara | Zendy; Tomowo Yoshida | Zendy; Hiroyuki Okada | Zendy; Kenji Yokota | Zendy; Keiji Oguma | Zendy

Open Access

A Better Cure Rate with 800 mg than with 400 mg Clarithromycin Regimens in One-Week Triple Therapy for <i>Helicobacter pylori </i>Infection in Cigarette-Smoking Peptic Ulcer Patients

Author(s) -

Hidehiko Ishioka,

Motowo Mizuno,

Susumu Take,

Kuniharu Ishiki,

Yasuhiro Nagahara,

Tomowo Yoshida,

Hiroyuki Okada,

Kenji Yokota,

Keiji Oguma

Publication year - 2007

Publication title -

digestion

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.882

H-Index - 75

eISSN - 1421-9867

pISSN - 0012-2823

DOI - 10.1159/000102301

Subject(s) - clarithromycin , helicobacter pylori , regimen , gastroenterology , medicine , lansoprazole , amoxicillin , proton pump inhibitor , antibiotics , microbiology and biotechnology , biology

In Helicobacter pylori eradication therapy, using a proton pump inhibitor plus amoxicillin and clarithromycin (PPI/AC regimen), the impact of the clarithromycin dose and smoking on efficacy is conflicting. Here, we compared the efficacy of 400 and 800 mg of clarithromycin in the regimen in relation to smoking in patients with peptic ulcer disease.

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