Variants in Scavenger Receptor Class B Type I Gene Are Associated with HDL Cholesterol Levels in Younger Women | Zendy

Caroline G. P. Roberts | Zendy; Haiqing Shen | Zendy; Braxton D. Mitchell | Zendy; Coleen Damcott | Zendy; Alan R. Shuldiner | Zendy; Annabelle Rodríguez | Zendy

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Variants in Scavenger Receptor Class B Type I Gene Are Associated with HDL Cholesterol Levels in Younger Women

Author(s) -

Caroline G. P. Roberts,

Haiqing Shen,

Braxton D. Mitchell,

Coleen Damcott,

Alan R. Shuldiner,

Annabelle Rodríguez

Publication year - 2007

Publication title -

human heredity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.423

H-Index - 62

eISSN - 1423-0062

pISSN - 0001-5652

DOI - 10.1159/000101962

Subject(s) - scavenger receptor , genetics , gene , biology , cholesterol , medicine , endocrinology , lipoprotein

Variants within the scavenger receptor class B type I (SCARB1) receptor gene have been previously associated with lipid levels, especially in women, with some studies reporting the association to be stronger in the presence of diabetes or post-menopausal estrogen use. Based on the reported gender-specific association and modification effect of estrogen on lipid levels according to SCARB1 variants, we explored the relationship between SCARBI single nucleotide polymorphisms (SNPs) and lipid levels in an Amish population to assess sex and age differences.

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