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Retinoblastoma Protein Prevents Staurosporine-Induced Cell Death in a Retinoblastoma-Defective Human Glioma Cell Line
Author(s) -
Fumiyuki Yamasaki,
Yoshinori Kajiwara,
Seiji Hama,
Taro Murakami,
Toshikazu Hidaka,
Taiichi Saito,
Hiroyuki Yoshioka,
Kazuhiko Sugiyama,
Kazunori Arita,
Kaoru Kurisu
Publication year - 2007
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000101048
Subject(s) - staurosporine , retinoblastoma , transfection , cell cycle , cell culture , programmed cell death , biology , multinucleate , microbiology and biotechnology , cell , cancer research , protein kinase c , apoptosis , kinase , gene , genetics
To investigate the mechanism of staurosporine-induced glioma cell death and cell cycle arrest using adenovirus-mediated gene transfection, as well as the function of retinoblastoma (Rb) and genetic instability induced by staurosporine.

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