Effects of a Synthetic Analog of Polycavernoside A on Human Neuroblastoma Cells | Zendy

Eva Cagide | Zendy; M. Carmen Louzao | Zendy; Isabel R. Ares | Zendy; Mercedes R. Vieytes | Zendy; Mari YotsuYamashita | Zendy; Leo A. Paquette | Zendy; Takeshi Yasumoto | Zendy; Luís M. Botana | Zendy

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Effects of a Synthetic Analog of Polycavernoside A on Human Neuroblastoma Cells

Author(s) -

Eva Cagide,

M. Carmen Louzao,

Isabel R. Ares,

Mercedes R. Vieytes,

Mari YotsuYamashita,

Leo A. Paquette,

Takeshi Yasumoto,

Luís M. Botana

Publication year - 2007

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000099206

Subject(s) - depolarization , extracellular , fura 2 , phalloidin , calcium , intracellular , biophysics , chemistry , muscarinic acetylcholine receptor , cytosol , microbiology and biotechnology , biochemistry , toxin , calcium in biology , membrane potential , biology , receptor , cytoskeleton , cell , organic chemistry , enzyme

Polycavernoside A is a glycosidic marine toxin first extracted from the red alga Polycavernosa tsudai in 1991 when 3 people died after the ingestion of this food. Polycavernoside A is an interesting molecule because of its complex macrolide structure and strong bioactivity. However, the target site of this toxin has not been characterized.

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