Glucagon-Like Peptide-1 Is Involved in Sodium and Water Homeostasis in Humans
Author(s) -
JeanPierre Gutzwiller,
Petr Hrúz,
Andreas Huber,
Christian Hamel,
C Zehnder,
Jürgen Drewe,
Heike Gutmann,
Zeno Stanga,
Daniel Vogel,
Christoph Beglinger
Publication year - 2006
Publication title -
digestion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.882
H-Index - 75
eISSN - 1421-9867
pISSN - 0012-2823
DOI - 10.1159/000094334
Subject(s) - medicine , endocrinology , saline , excretion , glucagon like peptide 1 , placebo , peptide yy , glucagon , sodium , glucose homeostasis , homeostasis , glucagon like peptide 2 , diabetes mellitus , chemistry , type 2 diabetes , receptor , insulin , insulin resistance , peptide , neuropeptide y receptor , neuropeptide , biochemistry , alternative medicine , organic chemistry , pathology
In previous studies with glucagon-like peptide-1 (GLP-1) we have observed that this peptide modulates fluid intake and increases renal sodium excretion in healthy volunteers and in patients with diabetes mellitus type 2. The effect of GLP-1 on thirst, water intake and on osmoregulation has, however, not been examined in detail in humans.
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