Modulating the Progression in IgA Nephropathy | Zendy

James C.M. Chan | Zendy; Howard Trachtman | Zendy

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Modulating the Progression in IgA Nephropathy

Author(s) -

James C.M. Chan,

Howard Trachtman

Publication year - 2006

Publication title -

nephron clinical practice

Language(s) - English

Resource type - Journals

ISSN - 1660-2110

DOI - 10.1159/000093672

Subject(s) - medicine , nephropathy , kidney disease , disease , tonsillectomy , population , nephrology , blockade , kidney , immunology , endocrinology , pathology , diabetes mellitus , receptor , environmental health

IgA nephropathy affects almost 1% of the population and yet the diagnosis is often missed. This significant kidney disease is often progressive with 25% of the patients going on to end-stage kidney disease over the course of 25 years. This minireview describes the clinical presentations in children and young adults. Therapeutic options are discussed including angiotensin-converting enzyme blockade, steroids, cytotoxics, tonsillectomy, fish oil, vitamin E, singly or in combination, in order to modulate the rate of progression.

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